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pasienter der blodet har nedsatt evne til å levre seg på grunn av blødersykdom eller blodfortynnende medisinerDisse fremstilles ved industriell behandling av ekstrakter fra valmue eller kjemisk produksjon uavhengig av opiumråstoff, for eksempel oksykodon og fentanyl.I vanskelige tilfeller av muskelsmerter, kan en lege foreskrive slike legemidle
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